What is Triple-Negative Breast Cancer?
When breast cancer cells test negative on three key markers, estrogen receptors, progesterone receptors and HER2 receptors, the cancer is called triple-negative.
This form of cancer, usually diagnosed in women before they reach the 40-50 age bracket, represents about 10-20% of all diagnosed breast cancers. It is more common among African-American or Hispanic women, and a particular gene mutation (BRCA1) also predisposes towards developing the cancer.
Triple-negative breast cancer certainly is beatable, but it presents a particular challenge because it does not respond to the hormone therapies used to treat other less aggressive forms of breast cancer and therefore can often require invasive surgeries such as full mastectomies over lumpectomies.
In addition, triple-negative cancer has shown itself more likely to spread and is more likely to re-occur after treatment during a 3-5 year window (however, it’s recurrence rate drops off below that of hormone responsive breast cancer after that period). Triple negative breast cancer also has a lower five-year survival rate than other forms of breast cancer.
For these reasons, finding a way to effectively tackle triple-negative breast cancer and improve the prognosis for sufferers has been a key area of investigation for the researchers.
There needs to be more awareness and research done on this particular sub-type of cancer and one of my goals with this blog is to bring more awareness to this disease so that it is better understood. I hope to see a cure for this disease in my lifetime.
Today, we are heading to the City to watch the Race for the Cure and cheer on our daughter who is running the race as an act of support in my battle. Looking forward to getting out with the crown and supporting the cause. Happy Sunday all <3